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Pembalap LCR Honda, Cal Crutchlow merajai sesi latihan bebas kedua GP Jerez, sedangkan sang juara bertahan Marc Marquez harus terjatuh.
Marquez memimpin sebagian besar sesi, tetapi memilih untuk tidak menggunakan ban belakang yang lunak di menit – menit akhir dan kemudian terjatuh di tikungan kekanan.
Setelah berada diposisi kedua saat latihan pertama dengan jarak hanya 0,007 detik, Marquez mencatat waktu terbaik pada lap ketiga FP2 untuk melampaui kecepatan FP1 Dovizioso.
| Pos. | # | Rider | Bike | Laps | Time | Gap |
|---|---|---|---|---|---|---|
| 1 | 35 | Cal Crutchlow | Honda | 20 | 1’38.614 | |
| 2 | 26 | Dani Pedrosa | Honda | 20 | 1’38.642 | 0.028 |
| 3 | 5 | Johann Zarco | Yamaha | 20 | 1’38.705 | 0.091 |
| 4 | 29 | Andrea Iannone | Suzuki | 21 | 1’38.709 | 0.095 |
| 5 | 93 | Marc Marquez | Honda | 19 | 1’38.863 | 0.249 |
| 6 | 4 | Andrea Dovizioso | Ducati | 20 | 1’39.068 | 0.454 |
| 7 | 99 | Jorge Lorenzo | Ducati | 19 | 1’39.076 | 0.462 |
| 8 | 43 | Jack Miller | Ducati | 17 | 1’39.102 | 0.488 |
| 9 | 46 | Valentino Rossi | Yamaha | 19 | 1’39.248 | 0.634 |
| 10 | 25 | Maverick Viñales | Yamaha | 19 | 1’39.514 | 0.900 |
| 11 | 44 | Pol Espargaro | KTM | 19 | 1’39.541 | 0.927 |
| 12 | 17 | Karel Abraham | Ducati | 19 | 1’39.541 | 0.927 |
| 13 | 42 | Alex Rins | Suzuki | 21 | 1’39.575 | 0.961 |
| 14 | 36 | Mika Kallio | KTM | 19 | 1’39.661 | 1.047 |
| 15 | 30 | Takaaki Nakagami | Honda | 21 | 1’39.694 | 1.080 |
| 16 | 9 | Danilo Petrucci | Ducati | 17 | 1’39.723 | 1.109 |
| 17 | 53 | Tito Rabat | Ducati | 24 | 1’39.888 | 1.274 |
| 18 | 38 | Bradley Smith | KTM | 19 | 1’39.948 | 1.334 |
| 19 | 21 | Franco Morbidelli | Honda | 18 | 1’39.951 | 1.337 |
| 20 | 19 | Alvaro Bautista | Ducati | 17 | 1’39.969 | 1.355 |
| 21 | 41 | Aleix Espargaro | Aprilia | 15 | 1’40.003 | 1.389 |
| 22 | 12 | Thomas Luthi | Honda | 17 | 1’40.241 | 1.627 |
| 23 | 55 | Hafizh Syahrin | Yamaha | 19 | 1’40.488 | 1.874 |
| 24 | 45 | Scott Redding | Aprilia | 15 | 1’40.536 | 1.922 |
| 25 | 10 | Xavier Simeon | Ducati | 17 | 1’40.663 | 2.049 |