Marc Marquez meraih start terdepan pada Grand Prix Jerman, sedangkan Danilo Petrucci dan Jorge Lorenzo menyusul ditempat kedua dan ketiga.
Marquez mengamankan posisi pole di Sachsenring untuk keenam kalinya di kelas utama, memperpanjang rekor pribadinya sendiri hingga sembilan kali, terhitung ketika ia berkompetisi pada kelas 125cc ditahun 2010. Berikut hasil lengkap kualifikasi MotoGP Sachsenring 2018:
| Pos | Rider | Team | Bike | Time | Gap |
|---|---|---|---|---|---|
| 1 | Marc Marquez | Honda | Honda | 1m20.270s | – |
| 2 | Danilo Petrucci | Pramac Ducati | Ducati | 1m20.295s | 0.025s |
| 3 | Jorge Lorenzo | Ducati | Ducati | 1m20.327s | 0.057s |
| 4 | Maverick Vinales | Yamaha | Yamaha | 1m20.441s | 0.171s |
| 5 | Andrea Dovizioso | Ducati | Ducati | 1m20.444s | 0.174s |
| 6 | Valentino Rossi | Yamaha | Yamaha | 1m20.532s | 0.262s |
| 7 | Cal Crutchlow | LCR Honda | Honda | 1m20.675s | 0.405s |
| 8 | Andrea Iannone | Suzuki | Suzuki | 1m20.682s | 0.412s |
| 9 | Alvaro Bautista | Aspar Ducati | Ducati | 1m20.700s | 0.430s |
| 10 | Dani Pedrosa | Honda | Honda | 1m20.831s | 0.561s |
| 11 | Alex Rins | Suzuki | Suzuki | 1m20.847s | 0.577s |
| 12 | Takaaki Nakagami | LCR Honda | Honda | 1m20.938s | 0.668s |
| 13 | Johann Zarco | Tech3 Yamaha | Yamaha | 1m21.059s | 0.789s |
| 14 | Jack Miller | Pramac Ducati | Ducati | 1m21.183s | 0.913s |
| 15 | Pol Espargaro | KTM | KTM | 1m21.242s | 0.972s |
| 16 | Bradley Smith | KTM | KTM | 1m21.287s | 1.017s |
| 17 | Hafizh Syahrin | Tech3 Yamaha | Yamaha | 1m21.460s | 1.190s |
| 18 | Tito Rabat | Avintia Ducati | Ducati | 1m21.546s | 1.276s |
| 19 | Aleix Espargaro | Aprilia | Aprilia | 1m20.972s | 0.702s |
| 20 | Scott Redding | Aprilia | Aprilia | 1m21.749s | 1.479s |
| 21 | Stefan Bradl | MVDS Honda | Honda | 1m21.802s | 1.532s |
| 22 | Thomas Luthi | MVDS Honda | Honda | 1m22.012s | 1.742s |
| 23 | Karel Abraham | Aspar Ducati | Ducati | 1m22.159s | 1.889s |
| 24 | Xavier Simeon | Avintia Ducati | Ducati | 1m22.709s | 2.439s |
