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Andrea Dovizioso meraih kemenangan di MotoGP Brno 2018, bersaing ketat dengan Jorge Lorenzo dan Marc Marquez.
Dovizioso dan Lorenzo membuktikan bahwa mereka mampu bersaing dibarisan depan, saling mendahului sebanyak lima kali dalam dua lap terakhir. Sementara itu Marquez saling mendahului dua kali dengan Lorenzo. Lorenzo mengklaim tempat kedua di lap terakhir setelah bersaing ketat dengan Marquez. Berikut hasil lengkap race MotoGP Brno 2018:
| Pos | Rider | Team | Bike | Gap |
|---|---|---|---|---|
| 1 | Andrea Dovizioso | Ducati | Ducati | 41m07.728s |
| 2 | Jorge Lorenzo | Ducati | Ducati | 0.178s |
| 3 | Marc Marquez | Honda | Honda | 0.368s |
| 4 | Valentino Rossi | Yamaha | Yamaha | 2.902s |
| 5 | Cal Crutchlow | LCR Honda | Honda | 2.958s |
| 6 | Danilo Petrucci | Pramac Ducati | Ducati | 3.768s |
| 7 | Johann Zarco | Tech3 Yamaha | Yamaha | 6.159s |
| 8 | Dani Pedrosa | Honda | Honda | 7.479s |
| 9 | Alvaro Bautista | Aspar Ducati | Ducati | 7.575s |
| 10 | Andrea Iannone | Suzuki | Suzuki | 8.326s |
| 11 | Alex Rins | Suzuki | Suzuki | 8.653s |
| 12 | Jack Miller | Pramac Ducati | Ducati | 16.549s |
| 13 | Franco Morbidelli | MVDS Honda | Honda | 19.603s |
| 14 | Hafizh Syahrin | Tech3 Yamaha | Yamaha | 21.381s |
| 15 | Aleix Espargaro | Aprilia | Aprilia | 23.159s |
| 16 | Thomas Luthi | MVDS Honda | Honda | 27.673s |
| 17 | Takaaki Nakagami | LCR Honda | Honda | 28.311s |
| 18 | Karel Abraham | Aspar Ducati | Ducati | 41.172s |
| 19 | Sylvain Guintoli | Suzuki | Suzuki | 42.411s |
| 20 | Xavier Simeon | Avintia Ducati | Ducati | 50.941s |
| – | Tito Rabat | Avintia Ducati | Ducati | Retirement |
| – | Scott Redding | Aprilia | Aprilia | Retirement |
| – | Bradley Smith | KTM | KTM | Crash |
| – | Stefan Bradl | Honda | Honda | Crash |
| – | Pol Espargaro | KTM | KTM | Withdrawn |
| – | Maverick Vinales | Yamaha | Yamaha | Crash |