Andrea Dovizioso tercepat FP1 MotoGP San Marino 2018, sementara Marc Marquez dan Valentino Rossi terlempar dari posisi 10 besar masing – masing diposisi 13 dan 15.
Setelah pembatalan race MotoGP Inggris karena hujan lebat. Kali ini FP1 MotoGP San Marino Misano 2018 berlangsung dalam kondisi cerah, dengan Dovizioso yang menjadi tercepat dengan catatan waktu 1 menit 32.608 detik. Berikut hasil lengkap FP1 MotoGP San Marino Misano 2018:
| Pos | Driver | Team | Time | Gap |
|---|---|---|---|---|
| 1 | Andrea Dovizioso | Ducati Team | 1:32.608 | |
| 2 | Cal Crutchlow | LCR Honda | 1:32.709 | 0.101 |
| 3 | Maverick Vinales | Yamaha MotoGP | 1:32.739 | 0.131 |
| 4 | Jorge Lorenzo | Ducati Team | 1:32.807 | 0.199 |
| 5 | Andrea Iannone | Suzuki Ecstar | 1:32.923 | 0.315 |
| 6 | Jack Miller | Pramac Racing | 1:33.193 | 0.585 |
| 7 | Dani Pedrosa | Honda Team | 1:33.209 | 0.601 |
| 8 | Johann Zarco | Yamaha Tech 3 | 1:33.241 | 0.633 |
| 9 | Danilo Petrucci | Pramac Racing | 1:33.255 | 0.647 |
| 10 | Franco Morbidelli | Marc VDS | 1:33.304 | 0.696 |
| 11 | Scott Redding | Aprilia Racing | 1:33.322 | 0.714 |
| 12 | Alvaro Bautista | Angel Nieto Team | 1:33.404 | 0.796 |
| 13 | Marc Marquez | Honda Team | 1:33.406 | 0.798 |
| 14 | Alex Rins | Suzuki Ecstar | 1:33.607 | 0.999 |
| 15 | Valentino Rossi | Yamaha MotoGP | 1:33.615 | 1.007 |
| 16 | Michele Pirro | Ducati Team | 1:33.696 | 1.088 |
| 17 | Takaaki Nakagami | LCR Honda | 1:33.843 | 1.235 |
| 18 | Bradley Smith | KTM Racing | 1:34.286 | 1.678 |
| 19 | Aleix Espargaro | Aprilia Racing | 1:34.544 | 1.936 |
| 20 | Stefan Bradl | Honda Team | 1:34.584 | 1.976 |
| 21 | Pol Espargaro | KTM Racing | 1:34.614 | 2.006 |
| 22 | Thomas Luthi | Marc VDS | 1:34.801 | 2.193 |
| 23 | Xavier Simeon | Avintia Racing | 1:34.967 | 2.359 |
| 24 | Karel Abraham | Angel Nieto Team | 1:35.077 | 2.469 |
| 25 | Hafizh Syahrin | Yamaha Tech 3 | 1:35.529 | 2.921 |
| 26 | Christophe Ponsson | Avintia Racing |
